Senior Principal Scientist
Company: Disability Solutions
Location: Brisbane
Posted on: May 3, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
careers.bms.com/working-with-us .Translational Medicine is part of
the Global Research and Early Development organization in BMS and
leads mid to late stage clinical, pharmacological, and
translational research and development activities for the BMS
hematology pipeline and supports late-stage portfolio for
translational development and life cycle management. Translational
Medicine Hematology at BMS has a long-standing history of
scientific rigor as evidenced by our peer-reviewed publications,
delivery of drug approvals including Revlimid, Pomalyst, Idhifa,
Inrebic, Reblozyl, Vidaza and Onureg, strong academic
collaborations and talent development. Our areas of focus include
but are not limited to Multiple Myeloma, Acute Myeloid
Leukemia/MDS, Lymphoma and Erythroid disorders. This group
integrates scientific learnings from the lab and clinic as well as
business insights of multiple functions and leads the development
of translational strategies at the franchise level. The Senior
Principal Scientist role will be responsible for development and
execution of drug and myeloma asset centric translational
strategies in hematology for assigned programs. Key
responsibilities of this role are to act as a lead asset scientist
to deliver and implement biomarker strategies for clinical programs
and influence programs regarding clinical implementation of novel
assays, identification of high-risk sub populations, patient
selection and combination strategies for our pipeline as well as
regulatory support including pre-clinical and translational
sections of NDA submissions. This individual will work on
cross-functional project teams to drive execution of
translational/biomarker plans working with laboratory and disease
scientists and BMS members from clinical, commercial, regulatory
and diagnostics as well as engage external academic
collaborators/Key opinion leaders (KOLs). This position can be
located in Summit, NJ or San Francisco, CA.Professional Skills:
- In-depth understanding of cancer biology/hematology, knowledge
of clinical landscape, evolving therapeutic landscape and
competitive scenarios
- Strong scientific background with understanding of clinical,
translational, and mechanistic data with proven track record of
publications
- Understanding of early or late-stage drug and translational
development process; including clinical trial experience in
industry or academia
- Protocol authoring and review of regulatory documents.
- Working knowledge of technological platforms covering biomarker
measures including but not limited to genomics, gene expression,
immune profiling, and flow cytometry.
- Proven ability to work with global disease teams to develop
drug development strategies
- Exceptional verbal and written communication skills with
experience in developing written documents such as primary
manuscripts/publications/reviews, disease strategies, scientific
presentations and regulatory submissions (INDs/NDAs)
- Proven scientific/project leadership expertise (working in
teams, managing people/projects)
- Excellent communication skills with ability to synthesize
complex scientific concepts into simple communication points
- Excellent data analysis and problem solving skills
- Agile to adapt to a fast paced work environment and changing
prioritiesResponsibilities:
- Leads the development of asset specific translational goals and
objectives for the Hematology Translational Medicine group
- Represents Translational Medicine (TM) on cross-functional
Strategy and Global Project Teams
- Oversees biomarker plan development and execution in clinical
trials and supports clinical trial operations in regard to
biomarker sampling
- Supports regulatory submissions, regulatory interactions,
writes translational sections for regulatory responses and answers
to regulatory queries for the TM group
- Participate/present data at scientific advisory boards to
support drug programs/projects
- Communicates regularly and prepares and makes presentations
within the department and externally as required
- Participates in translational research with the hematology
laboratory and disease teams
- Responsible for selection and delivery of Clinical PD or
Biomarker assays including assessing the need and applicability for
companion/complementary diagnostics for asset programs
- May participate in BD and established teams to evaluate the
potential in-licensing opportunities that will advance our Drug
Discovery and Development pipeline
- May perform advisory and mentoring role for junior
scientists
- Assists in developing and maintaining group budget and
workforce planBasic Qualifications:
- Bachelor's Degree
- 10+ years of academic and / or industry experienceOr
- Master's Degree
- 8+ years of academic and / or industry experienceOr
- Ph.D. or equivalent advanced degree in the Life Sciences
- 6+ years of academic and / or industry experience
- 2+ years of leadership experiencePreferred Qualifications:
- PhD in Hematology/Oncology or related field with min 6-8 years
in industry and academic setting
- Track record in drug discovery/development in large or small
biotech/pharmaceutical companies, leading translational/biomarker
studies or innovative efforts to deploy technologies and assays for
enhanced translational capabilities or similar skill sets in
academia
- Experience with translational/biomarker strategies for early or
late stage clinical trials or investigator sponsored trials in
academiaThe starting compensation for this job is a range from
$159,000 - $200,000, plus incentive cash and stock opportunities
(based on eligibility). The starting pay takes into account
characteristics of the job, such as required skills and where the
job is performed. Final, individual compensation is decided based
on demonstrated experience. For more on benefits, please visit our
BMS Careers site. Eligibility for specific benefits listed in our
careers site may vary based on the job and location.If you come
across a role that intrigues you but doesn't perfectly line up with
your resume, we encourage you to apply anyway. You could be one
step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing CareersWith a single
vision as inspiring as Transforming patients' lives through
science--- , every BMS employee plays an integral role in work that
goes far beyond ordinary. Each of us is empowered to apply our
individual talents and unique perspectives in an inclusive culture,
promoting diversity in clinical trials, while our shared values of
passion, innovation, urgency, accountability, inclusion and
integrity bring out the highest potential of each of our
colleagues.On-site Protocol BMS has a diverse occupancy structure
that determines where an employee is required to conduct their
work. This structure includes site-essential, site-by-design,
field-based and remote-by-design jobs. The occupancy type that you
are assigned is determined by the nature and responsibilities of
your role: Site-essential roles require 100% of shifts onsite at
your assigned facility. Site-by-design roles may be eligible for a
hybrid work model with at least 50% onsite at your assigned
facility. For these roles, onsite presence is considered an
essential job function and is critical to collaboration,
innovation, productivity, and a positive Company culture. For
field-based and remote-by-design roles the ability to physically
travel to visit customers, patients or business partners and to
attend meetings on behalf of BMS as directed is an essential job
function. BMS is dedicated to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace accommodations/adjustments and ongoing support
in their roles. Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/
eeo -accessibility to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your
area.Any data processed in connection with role applications will
be treated in accordance with applicable data privacy policies and
regulations.
Keywords: Disability Solutions, Richmond , Senior Principal Scientist, Other , Brisbane, California
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